What is the primary pathophysiological mechanism of hypoxic hypoxia in aviation, and which altitude range is associated with the 'indifferent zone' where symptoms are minimal?
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A
Reduced hemoglobin oxygen-carrying capacity; sea level to 10,000 feet
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B
Reduced partial pressure of inspired oxygen causing decreased alveolar and arterial oxygen; sea level to 10,000 feet
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C
Carbon monoxide binding to hemoglobin; sea level to 5,000 feet
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D
Reduced respiratory rate from high altitude anxiety; sea level to 8,000 feet