AGD Oral Pathology and Diagnosis 4

Question 1

A 55-year-old with HIV presents with a white, corrugated lesion on the lateral border of the tongue that cannot be wiped off. EBV is implicated. What is the diagnosis?

Accepted Answer

Hairy leukoplakia

Answer

Oral hairy leukoplakia is caused by EBV replication in keratinocytes and presents as a corrugated or 'hairy' white lesion on the lateral tongue that cannot be removed by wiping.

Question 2

Langerhans cell histiocytosis involving the jaw is MOST likely to present radiographically as:

Accepted Answer

Floating teeth appearance due to alveolar bone destruction

Answer

Langerhans cell histiocytosis causes rapid alveolar bone destruction that gives teeth the appearance of floating in space on radiographs.

Question 3

A patient presents with burning mouth, angular cheilitis, and a smooth, atrophic, erythematous tongue. Lab results show low serum iron and ferritin. What oral manifestation pattern is this?

Accepted Answer

Plummer-Vinson syndrome

Answer

Plummer-Vinson syndrome presents with iron-deficiency anemia, dysphagia from esophageal webs, glossitis, and angular cheilitis, and carries increased risk for oral and esophageal carcinoma.

Question 4

Which of the following is TRUE regarding central giant cell granuloma (CGCG) of the jaws?

Accepted Answer

It cannot be distinguished from hyperparathyroidism lesions by histology alone

Answer

Central giant cell granuloma and the brown tumor of hyperparathyroidism are histologically identical; clinical and laboratory correlation is essential for differentiation.

Question 5

A painful vesiculoulcerative lesion affecting the hard palate and attached gingiva with subepithelial bullae and linear IgA deposits at the basement membrane zone on direct immunofluorescence is MOST consistent with:

Accepted Answer

Mucous membrane pemphigoid

Answer

Mucous membrane pemphigoid shows subepithelial clefting with IgG, IgA, or C3 deposits at the BMZ on DIF and preferentially affects mucosal sites, especially gingiva (desquamative gingivitis) and palate.

(AGD) Academy of General Dentistry Certification Practice Test

(AGD) Academy of General Dentistry Certification Practice Test

AGD Oral Pathology and Diagnosis 4