FREE AGD Oral Pathology and Diagnosis Questions and Answers

Question 1

A 65-year-old male, a long-term heavy smoker, presents with a persistent, well-demarcated white patch on the lateral border of his tongue.
The lesion is asymptomatic and cannot be wiped off with gauze.
What is the most appropriate next step in management?

Accepted Answer

Perform an incisional biopsy for definitive histopathologic diagnosis.

Answer

Prescribe a topical antifungal medication and re-evaluate in two weeks.

Answer

Advise the patient to cease smoking and observe the lesion for 3 months.

Answer

Recommend a chlorhexidine gluconate rinse to improve oral hygiene.

Question 2

Which of the following odontogenic cysts is most noted for its aggressive clinical behavior, high recurrence rate, and its association with Nevoid Basal Cell Carcinoma Syndrome (Gorlin-Goltz Syndrome)?

Accepted Answer

Odontogenic Keratocyst (OKC)

Answer

Radicular (Periapical) Cyst

Answer

Dentigerous Cyst

Answer

Calcifying Odontogenic Cyst

Question 3

A panoramic radiograph of a 48-year-old asymptomatic African American female reveals multiple, bilateral, well-defined, mixed radiolucent/radiopaque lesions located in the periapical regions of the mandibular teeth. All associated teeth test vital. What is the most likely diagnosis?

Accepted Answer

Florid Cemento-Osseous Dysplasia

Answer

Chronic Diffuse Sclerosing Osteomyelitis

Answer

Multiple Periapical Granulomas

Answer

Paget's Disease of Bone

Question 4

A patient presents with painful, sloughing oral lesions. A biopsy is taken for direct immunofluorescence, which reveals IgG and C3 deposits in an intercellular, 'fishnet-like' pattern throughout the epithelium. This finding is pathognomonic for which of the following conditions?

Accepted Answer

Pemphigus Vulgaris

Answer

Bullous Pemphigoid

Answer

Erosive Lichen Planus

Answer

Erythema Multiforme

Question 5

A 35-year-old patient has a solitary, flat, blue-gray macule on the mandibular gingiva adjacent to a tooth with a large amalgam restoration. The lesion is asymptomatic and has been present for years without any change. What is the most likely diagnosis?

Accepted Answer

Amalgam Tattoo (Focal Argyrosis)

Answer

Melanotic Macule

Answer

Blue Nevus

Answer

Malignant Melanoma

Question 6

Which of the following is the most common benign salivary gland tumor, typically presenting as a slow-growing, painless, mobile mass most often in the parotid gland?

Accepted Answer

Pleomorphic Adenoma

Answer

Warthin Tumor

Answer

Mucoepidermoid Carcinoma

Answer

Adenoid Cystic Carcinoma

A 65-year-old male, a long-term heavy smoker, presents with a persistent, well-demarcated white patch on the lateral border of his tongue.The lesion is asymptomatic and cannot be wiped off with gauze.What is the most appropriate next step in management?

A 65-year-old male, a long-term heavy smoker, presents with a persistent, well-demarcated white patch on the lateral border of his tongue.
The lesion is asymptomatic and cannot be wiped off with gauze.
What is the most appropriate next step in management?