AGD Oral Pathology and Diagnosis 4

Question 1

A 55-year-old with HIV presents with a white, corrugated lesion on the lateral border of the tongue that cannot be wiped off. EBV is implicated. What is the diagnosis?

Accepted Answer

Hairy leukoplakia

Answer

Pseudomembranous candidiasis

Answer

Lichen planus

Answer

White sponge nevus

Question 2

Langerhans cell histiocytosis involving the jaw is MOST likely to present radiographically as:

Accepted Answer

Floating teeth appearance due to alveolar bone destruction

Answer

Ground-glass opacity with cortical expansion

Answer

Multilocular radiolucency with internal bony septa

Answer

Diffuse sclerosis of the mandible

Question 3

A patient presents with burning mouth, angular cheilitis, and a smooth, atrophic, erythematous tongue. Lab results show low serum iron and ferritin. What oral manifestation pattern is this?

Accepted Answer

Plummer-Vinson syndrome

Answer

Sjögren syndrome

Answer

Pernicious anemia

Answer

Pellagra

Question 4

Which of the following is TRUE regarding central giant cell granuloma (CGCG) of the jaws?

Accepted Answer

It cannot be distinguished from hyperparathyroidism lesions by histology alone

Answer

It is a true neoplasm derived from osteoclasts

Answer

It is more aggressive than the giant cell tumor of long bones

Answer

It is more common in young females and anterior mandible

Question 5

A painful vesiculoulcerative lesion affecting the hard palate and attached gingiva with subepithelial bullae and linear IgA deposits at the basement membrane zone on direct immunofluorescence is MOST consistent with:

Accepted Answer

Mucous membrane pemphigoid

Answer

Pemphigus vulgaris

Answer

Epidermolysis bullosa acquisita

Answer

Dermatitis herpetiformis

Question 6

Which of the following best describes the histopathologic appearance of a mucocele (mucous extravasation phenomenon)?

Accepted Answer

Pool of mucin surrounded by granulation tissue without an epithelial lining

Answer

Cyst lined by mucous secreting columnar epithelium

Answer

Dilated duct filled with inspissated mucin and lined by ductal epithelium

Answer

Pseudostratified columnar epithelial lining with mucous goblet cells

Question 7

A 70-year-old edentulous patient presents with a progressive, painful swelling of the mandible. CT shows ill-defined bone destruction with periosteal reaction. Biopsy reveals nests of malignant squamous cells invading bone. What is the most likely primary source?

Accepted Answer

Primary intraosseous squamous cell carcinoma

Answer

Metastatic lung carcinoma

Answer

Osteosarcoma of jaw

Answer

Ewing sarcoma