ABPath Blood Banking and Transfusion 2

Question 1

A patient's serum reacts with all reagent red cells in an antibody panel including the autocontrol. What is the most likely cause?

Accepted Answer

A warm autoantibody

Answer

Anti-K alloantibody

Answer

A single low-frequency antibody

Answer

Rouleaux only

Question 2

Which blood group system antigen is destroyed by treating red cells with proteolytic enzymes like ficin?

Accepted Answer

Fya (Duffy)

Answer

Jka (Kidd)

Answer

K (Kell)

Answer

E (Rh)

Question 3

A group O mother delivers a group A infant with a positive DAT and jaundice at birth. What is the most likely diagnosis?

Accepted Answer

ABO hemolytic disease of the newborn

Answer

Rh hemolytic disease

Answer

Hereditary spherocytosis

Answer

G6PD deficiency

Question 4

What is the minimum hemoglobin concentration typically required for an allogeneic whole blood donor in the US?

Accepted Answer

12.5 g/dL

Answer

10.0 g/dL

Answer

13.0 g/dL

Answer

11.0 g/dL

Question 5

A febrile nonhemolytic transfusion reaction is most commonly caused by which mechanism?

Accepted Answer

Cytokines from donor leukocytes and recipient antibodies to leukocytes

Answer

ABO incompatibility

Answer

IgA deficiency

Answer

Bacterial contamination

Question 6

Which component is the treatment of choice for fibrinogen replacement in a bleeding patient with hypofibrinogenemia?

Accepted Answer

Cryoprecipitate

Answer

Packed red blood cells

Answer

Platelets

Answer

Albumin

Question 7

At what temperature must red blood cell units be stored during refrigerated storage?

Accepted Answer

1 to 6°C

Answer

20 to 24°C

Answer

-18°C or colder

Answer

10 to 15°C