ABOG ABOG Gynecologic Oncology & Cancer Management 2

Question 1

A patient with vulvar cancer requires a sentinel lymph node biopsy. What is the preferred mapping agent used in the United States?

Accepted Answer

Technetium-99m with blue dye

Answer

Technetium-99m radiocolloid combined with blue dye (isosulfan blue or methylene blue) is the standard dual-mapping technique for sentinel lymph node biopsy in vulvar cancer.

Question 2

Which hereditary syndrome is most strongly associated with ovarian and endometrial cancer risk?

Accepted Answer

Lynch syndrome (HNPCC)

Answer

Lynch syndrome (hereditary nonpolyposis colorectal cancer) confers a 40–60% lifetime risk of endometrial cancer and 10–12% risk of ovarian cancer due to mismatch repair gene mutations.

Question 3

What is the standard chemotherapy regimen for advanced epithelial ovarian cancer after cytoreductive surgery?

Accepted Answer

Carboplatin and paclitaxel

Answer

Carboplatin plus paclitaxel (every 3 weeks for 6 cycles) is the standard first-line chemotherapy regimen for advanced epithelial ovarian cancer.

Question 4

In gestational trophoblastic neoplasia (GTN), which single-agent chemotherapy is used for low-risk disease?

Accepted Answer

Methotrexate

Answer

Methotrexate (with or without folinic acid rescue) is the preferred single-agent chemotherapy for low-risk gestational trophoblastic neoplasia due to high cure rates and favorable toxicity profile.

Question 5

A Pap smear shows HSIL. After colposcopy confirms CIN 3, what is the standard treatment?

Accepted Answer

Loop electrosurgical excision procedure (LEEP)

Answer

LEEP (loop electrosurgical excision procedure) is the standard treatment for CIN 3 as it provides both treatment and a tissue specimen for pathologic evaluation.

(ABOG) American Board of Obstetrics & Gynecology Practice Test

(ABOG) American Board of Obstetrics & Gynecology Practice Test

ABOG ABOG Gynecologic Oncology & Cancer Management 2