ABOG ABOG Oncology & Gynecologic Cancers 1

Question 1

Which HPV genotypes are most commonly associated with cervical squamous cell carcinoma?

Accepted Answer

HPV 16 and 18

Answer

HPV 6 and 11

Answer

HPV 31 and 33 only

Answer

HPV 45 and 52 only

Question 2

What is the recommended first-line treatment for early-stage (IA1 without lymphovascular invasion) cervical cancer in a patient desiring fertility preservation?

Accepted Answer

Conization alone

Answer

Radical hysterectomy

Answer

Pelvic radiation

Answer

Chemotherapy alone

Question 3

Which histologic type of endometrial cancer carries the worst prognosis?

Accepted Answer

Uterine serous carcinoma

Answer

Endometrioid grade 1

Answer

Mucinous adenocarcinoma

Answer

Squamous cell carcinoma

Question 4

A patient with ovarian cancer has a BRCA1 germline mutation. Which maintenance therapy is most appropriate after platinum-based chemotherapy?

Accepted Answer

PARP inhibitor (olaparib)

Answer

Bevacizumab alone

Answer

Tamoxifen

Answer

Letrozole

Question 5

Which tumor marker is most useful for monitoring treatment response in epithelial ovarian cancer?

Accepted Answer

CA-125

Answer

AFP

Answer

CEA

Answer

HCG

Question 6

What is the Lynch syndrome-associated endometrial cancer lifetime risk compared to the general population?

Accepted Answer

Substantially elevated (40–60%)

Answer

Slightly elevated (10–15%)

Answer

Moderately elevated (20–30%)

Answer

No increased risk