Trivium Pharmacology Fundamentals 3

Question 1

Which type of drug interaction occurs when one drug increases the effect of another beyond what either would produce alone?

Accepted Answer

Potentiation

Answer

Potentiation occurs when one drug enhances the effect of another drug that has little or no effect by itself.

Question 2

What does 'PRN' mean on a medication order?

Accepted Answer

As needed

Answer

PRN comes from the Latin 'pro re nata,' meaning 'as needed' or 'as the situation demands.'

Question 3

A patient develops tolerance to a drug. This means:

Accepted Answer

Increased doses are needed to achieve the same effect

Answer

Tolerance occurs when the body adapts to a drug over time, requiring higher doses to produce the original therapeutic effect.

Question 4

Which administration route bypasses the first-pass effect?

Accepted Answer

Intravenous

Answer

Intravenous administration delivers drugs directly to systemic circulation, completely bypassing hepatic first-pass metabolism.

Question 5

What is a 'loading dose'?

Accepted Answer

A higher initial dose given to quickly reach therapeutic levels

Answer

A loading dose is a larger-than-normal initial dose used to rapidly achieve a therapeutic plasma concentration.

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