TBI TBI Pharmacological Management 2

Question 1

Propranolol is sometimes used post-TBI primarily to treat which condition?

Accepted Answer

Autonomic dysreflexia and sympathetic storming

Answer

Depression

Answer

Cognitive fatigue

Answer

Hydrocephalus

Question 2

Which medication is avoided in TBI due to its potential to lower the seizure threshold?

Accepted Answer

Tramadol

Answer

Memantine

Answer

Baclofen

Answer

Modafinil

Question 3

What is the role of methylphenidate in post-acute TBI rehabilitation?

Accepted Answer

Improve attention, processing speed, and cognitive fatigue

Answer

Reduce intracranial pressure

Answer

Treat spasticity

Answer

Prevent late post-traumatic epilepsy

Question 4

Hypertonic saline is used in TBI management primarily as an alternative to which drug?

Accepted Answer

Mannitol

Answer

Dexamethasone

Answer

Phenytoin

Answer

Dopamine

Question 5

Why is corticosteroid use (e.g., dexamethasone) contraindicated in acute TBI?

Accepted Answer

The CRASH trial showed increased mortality with corticosteroids in TBI

Answer

They cause hypoglycemia

Answer

They worsen spasticity

Answer

They reduce CSF absorption

Question 6

Which medication is used to manage spasticity following TBI by acting as a GABA-B receptor agonist?

Accepted Answer

Baclofen

Answer

Tizanidine

Answer

Diazepam

Answer

Dantrolene