SNLE Pharmacology

Question 1

What is the meaning of 'therapeutic index'?

Accepted Answer

The ratio between the toxic dose and the therapeutic dose of a drug

Answer

The speed of drug absorption

Answer

The route of drug administration

Answer

The duration of drug action

Question 2

Which phase of pharmacokinetics describes the breakdown of a drug into metabolites?

Accepted Answer

Metabolism (biotransformation)

Answer

Absorption

Answer

Distribution

Answer

Excretion

Question 3

A patient is taking digoxin. Which electrolyte imbalance increases the risk of digoxin toxicity?

Accepted Answer

Hypokalemia (low potassium)

Answer

Hyperkalemia

Answer

Hypernatremia

Answer

Hypercalcemia

Question 4

What is the antidote for acetaminophen (paracetamol) overdose?

Accepted Answer

N-acetylcysteine (NAC)

Answer

Naloxone

Answer

Flumazenil

Answer

Activated charcoal only

Question 5

A patient is prescribed metformin for type 2 diabetes. What is the most serious adverse effect to monitor for?

Accepted Answer

Lactic acidosis, particularly in renal impairment

Answer

Hypoglycemia

Answer

Weight gain

Answer

Sodium retention

Question 6

Which drug class can cause hyperkalemia?

Accepted Answer

ACE inhibitors and potassium-sparing diuretics

Answer

Loop diuretics

Answer

Thiazide diuretics

Answer

Calcium channel blockers