A hospital pharmacy is implementing an antibiotic stewardship program (ASP). Which pharmacist-led intervention has the strongest evidence for reducing antibiotic overuse?
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A
Prospective audit and feedback — pharmacist reviews antibiotic prescriptions and provides real-time recommendations to prescribers
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B
Antibiotic restriction requiring pre-approval for all antibiotics
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C
Educational lectures to physicians without feedback
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D
Automatic antibiotic stop orders at 48 hours for all infections