Pharmacology & Treatment Protocols Flashcards
7 cards from real Radiation Health and Safety Test practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Pharmacology & Treatment Protocols flashcards as text
Iodine-131 is used therapeutically for hyperthyroidism and thyroid cancer chiefly because it:
Answer: Emits beta particles that destroy thyroid tissue
I-131 is concentrated by thyroid tissue and its beta emission delivers local therapeutic dose.
What is the physical half-life of Tc-99m, the most widely used diagnostic radionuclide?
Answer: About 6 hours
Tc-99m has a half-life of roughly 6 hours, balancing imaging time against patient dose.
F-18 FDG PET imaging relies on FDG being an analog of which molecule?
Answer: Glucose
FDG is taken up like glucose by metabolically active cells but is trapped after phosphorylation.
Radium-223 dichloride, an alpha-emitting therapy, is approved to treat:
Answer: Bone metastases in castration-resistant prostate cancer
Radium mimics calcium and localizes to bone metastases, delivering high-LET alpha radiation locally.
Strontium-89 and samarium-153 are used for which indication?
Answer: Palliation of painful bone metastases
These bone-seeking beta emitters relieve pain from osteoblastic skeletal metastases.
Before administering I-131 therapy to a woman of childbearing age, what must be done?
Answer: Confirm she is not pregnant
I-131 crosses the placenta and the fetal thyroid takes it up, so pregnancy must be excluded.
Lutetium-177 PSMA therapy delivers radiation by:
Answer: Binding to PSMA-expressing prostate cancer cells
The ligand targets prostate-specific membrane antigen, delivering beta radiation to the tumor cells.
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