Pharmacology & Treatment Protocols Flashcards
7 cards from real Radiation Health and Safety Test practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Pharmacology & Treatment Protocols flashcards as text
Filgrastim (G-CSF) is used in hematopoietic acute radiation syndrome primarily to:
Answer: Stimulate neutrophil production
G-CSF accelerates neutrophil recovery and shortens neutropenia in patients with marrow suppression.
Which early lab finding is a useful biodosimetry indicator in the first 24 to 48 hours after suspected acute exposure?
Answer: Serial absolute lymphocyte count
Lymphocytes are highly radiosensitive and a rapid fall in count correlates with higher absorbed dose.
Which drug class is commonly used to treat nausea and vomiting in the prodromal phase of ARS?
Answer: 5-HT3 antagonists such as ondansetron
Serotonin 5-HT3 antagonists are the standard antiemetics for radiation-induced nausea and vomiting.
What is the first step in decontaminating a patient with external radioactive contamination?
Answer: Remove outer clothing and shoes
Removing clothing eliminates most external contamination quickly and with minimal risk of spreading it.
Amifostine is used in radiation oncology as a:
Answer: Cytoprotective agent reducing xerostomia
Amifostine scavenges free radicals in normal tissue and reduces salivary gland toxicity in head and neck radiotherapy.
Supportive care for the gastrointestinal subsyndrome of ARS centers on:
Answer: Fluid and electrolyte replacement with infection control
GI injury causes fluid and electrolyte loss and bacterial translocation, so replacement and antimicrobials are the core of management.
What is the recommended approach for reducing the biological half-life of internal tritium (tritiated water) contamination?
Answer: Increase fluid intake to promote diuresis
Forced fluids dilute body water and shorten the biological half-life of tritiated water.
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