PSI Pharmaceutical Sciences

Question 1

Which route of administration provides 100% bioavailability?

Accepted Answer

Intravenous

Answer

Oral

Answer

Intramuscular

Answer

Subcutaneous

Question 2

What is the Henderson-Hasselbalch equation used to calculate?

Accepted Answer

pH of a buffer solution

Answer

Osmolarity of a solution

Answer

Partition coefficient

Answer

Solubility product

Question 3

Which process describes drug movement from high to low concentration without energy expenditure?

Accepted Answer

Passive diffusion

Answer

Active transport

Answer

Endocytosis

Answer

Facilitated transport

Question 4

The volume of distribution (Vd) of a highly lipophilic drug is typically:

Accepted Answer

Large, as drug distributes into tissues

Answer

Small, as drug stays in plasma

Answer

Equal to total body water

Answer

Equal to plasma volume

Question 5

Which excipient acts as a disintegrant in tablet formulations?

Accepted Answer

Croscarmellose sodium

Answer

Magnesium stearate

Answer

Lactose monohydrate

Answer

Povidone

Question 6

First-pass metabolism predominantly occurs in which organ?

Accepted Answer

Liver

Answer

Kidney

Answer

Lung

Answer

Stomach