Dermatologic System Disorders Flashcards
7 cards from real Physician Assistant practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Dermatologic System Disorders flashcards as text
Which histologic feature is the most important prognostic factor in a newly diagnosed localized cutaneous melanoma?
Answer: Breslow thickness
Breslow depth (thickness in mm) is the strongest prognostic factor for localized melanoma and guides staging.
A family presents with intensely pruritic papules in finger web spaces and burrows on the wrists, worse at night. What is first-line treatment?
Answer: Permethrin 5% cream applied neck down, repeated in 1 week
Permethrin 5% is first-line for scabies, with treatment of all close contacts and a repeat application in 7-14 days.
A 28-year-old has tender red nodules on both anterior shins and bilateral hilar lymphadenopathy on chest x-ray. Which condition is most likely?
Answer: Sarcoidosis
Erythema nodosum with bilateral hilar adenopathy (Löfgren syndrome) suggests sarcoidosis.
A patient has pruritic, purple, polygonal, flat-topped papules on the wrists with fine white lacy lines (Wickham striae). Which infection should be screened for?
Answer: Hepatitis C
Lichen planus has a well-documented association with hepatitis C infection.
Which acne medication requires enrollment in the iPLEDGE program with two forms of contraception and monthly pregnancy tests?
Answer: Isotretinoin
Isotretinoin is highly teratogenic, so US prescribing is restricted through iPLEDGE.
A KOH prep of hypopigmented scaly macules on the upper back shows a 'spaghetti and meatballs' pattern. Which organism is responsible?
Answer: Malassezia furfur
Tinea (pityriasis) versicolor is caused by Malassezia yeast showing short hyphae and spores on KOH.
Velvety, hyperpigmented plaques on the posterior neck and axillae of an obese adolescent most strongly suggest which underlying condition?
Answer: Insulin resistance
Acanthosis nigricans is most commonly associated with insulin resistance and obesity.
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