Physician Assistant Physician Assistant Neurological System Disorders 2

Question 1

A 70-year-old presents with progressive resting tremor, bradykinesia, and cogwheel rigidity. What is the most likely diagnosis?

Accepted Answer

Parkinson's disease

Answer

Essential tremor

Answer

Wilson's disease

Answer

Huntington's disease

Question 2

Which neurotransmitter is deficient in Parkinson's disease?

Accepted Answer

Dopamine

Answer

Serotonin

Answer

Acetylcholine

Answer

GABA

Question 3

A patient presents with sudden severe headache, nuchal rigidity, photophobia, and fever. CSF analysis shows cloudy fluid, elevated protein, low glucose, and neutrophilic pleocytosis. What is the most appropriate immediate treatment?

Accepted Answer

IV ceftriaxone and dexamethasone empirically

Answer

Await culture results before starting antibiotics

Answer

Oral amoxicillin and close outpatient follow-up

Answer

IV acyclovir only

Question 4

Which type of seizure is characterized by sudden loss of muscle tone causing the patient to fall?

Accepted Answer

Atonic seizure

Answer

Absence seizure

Answer

Myoclonic seizure

Answer

Tonic-clonic seizure

Question 5

A 30-year-old with epilepsy presents in status epilepticus. After two doses of lorazepam, seizures persist. What is the next pharmacological treatment?

Accepted Answer

IV levetiracetam or fosphenytoin

Answer

Oral phenytoin

Answer

Oral valproate

Answer

Repeat lorazepam indefinitely

Question 6

A 50-year-old presents with symmetric ascending weakness and areflexia following a GI infection 3 weeks prior. CSF shows albuminocytologic dissociation. What is the most likely diagnosis?

Accepted Answer

Guillain-Barré syndrome

Answer

Multiple sclerosis

Answer

Myasthenia gravis

Answer

Amyotrophic lateral sclerosis