A hospitalized patient on IV ciprofloxacin is transitioned to oral ciprofloxacin for continued treatment. The physician asks if a dose adjustment is needed. What is the best response?
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A
Reduce the dose by 50% because oral absorption is poor
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B
No adjustment needed; ciprofloxacin has approximately 70–80% oral bioavailability
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C
Double the oral dose to compensate for first-pass metabolism
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D
Avoid oral ciprofloxacin in hospitalized patients