PTCB Pharmacology #4 3 Flashcards
6 cards from real Pharmacy practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 PTCB Pharmacology #4 3 flashcards as text
Which drug suffix indicates a "-statin" belongs to the HMG-CoA reductase inhibitor class?
Answer: -vastatin
All HMG-CoA reductase inhibitors end in "-vastatin" (atorvastatin, rosuvastatin, simvastatin, pravastatin, lovastatin, fluvastatin, pitavastatin).
Naloxone works by:
Answer: Competitively blocking opioid receptors
Naloxone (Narcan) is a competitive opioid receptor antagonist that rapidly displaces opioids from mu, kappa, and delta receptors, reversing respiratory depression, sedation, and analgesia within 2–5 minutes.
Which drug is a selective serotonin-1A partial agonist used for generalized anxiety disorder?
Answer: Buspirone
Buspirone (Buspar) is a 5-HT1A partial agonist used for GAD. Unlike benzodiazepines, it has no abuse potential, no sedation, and requires 2–4 weeks for full anxiolytic effect.
Digoxin toxicity can be precipitated by which electrolyte imbalance?
Answer: Hypokalemia
Hypokalemia (low potassium) increases digoxin toxicity because potassium and digoxin compete for the same binding site on Na+/K+ ATPase. Diuretic-induced hypokalemia is a common precipitant of toxicity.
Which of the following describes "tolerance" in pharmacology?
Answer: The need for increasing doses to achieve the same effect with repeated use
Tolerance is the reduced pharmacological response to a drug after repeated administration, requiring higher doses to achieve the original effect. It is common with opioids, benzodiazepines, and nitrates.
Which drug class includes drugs ending in "-tidine" (e.g., famotidine, ranitidine)?
Answer: H2 receptor antagonists
H2 receptor antagonists (H2 blockers) end in "-tidine" (famotidine/Pepcid, ranitidine/Zantac, cimetidine/Tagamet). They competitively block histamine H2 receptors on parietal cells, reducing acid secretion.