PTCB Pharmacology #2 2 Flashcards
6 cards from real Pharmacy practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 PTCB Pharmacology #2 2 flashcards as text
Which drug suffix is characteristic of calcium channel blockers (dihydropyridine class)?
Answer: -dipine
Dihydropyridine calcium channel blockers end in "-dipine" (amlodipine, nifedipine, felodipine). Non-dihydropyridines (verapamil, diltiazem) have different suffixes.
Albuterol (ProAir, Ventolin) primarily acts on which receptor?
Answer: Beta-2 adrenergic
Albuterol is a selective beta-2 adrenergic agonist that causes bronchodilation by relaxing airway smooth muscle. It is the most common rescue inhaler for asthma and COPD.
Which term describes a drug that binds to a receptor and produces a response?
Answer: Agonist
An agonist binds to a receptor and activates it to produce a pharmacological response. An antagonist binds but does not activate the receptor, blocking agonist effects.
Loop diuretics like furosemide primarily cause loss of which electrolyte?
Answer: Potassium and sodium
Loop diuretics cause loss of sodium, chloride, potassium, magnesium, and calcium. Hypokalemia is the most clinically significant electrolyte disturbance, requiring monitoring and supplementation.
Which class of antibiotic inhibits cell wall synthesis by binding to penicillin-binding proteins (PBPs)?
Answer: Beta-lactams
Beta-lactam antibiotics (penicillins, cephalosporins, carbapenems) inhibit bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBPs).
What is the term for the concentration of a drug at which 50% of the maximum response is achieved?
Answer: ED50 (EC50)
EC50 (or ED50) is the drug concentration (or dose) producing 50% of maximal effect on the dose-response curve. LD50 = lethal dose in 50% of animals; TD50 = toxic dose in 50%.