Pharmacology Flashcards
6 cards from real Pharmacy practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 Pharmacology flashcards as text
What is the mechanism of action of ACE inhibitors in treating hypertension?
Answer: Inhibit the conversion of angiotensin I to angiotensin II
ACE inhibitors block angiotensin-converting enzyme, preventing formation of angiotensin II (a potent vasoconstrictor), reducing blood pressure.
SSRIs are first-line treatment for depression because they selectively inhibit reuptake of which neurotransmitter?
Answer: Serotonin
SSRIs (Selective Serotonin Reuptake Inhibitors) block serotonin reuptake transporters, increasing serotonin availability in the synapse.
Warfarin inhibits which vitamin to exert its anticoagulant effect?
Answer: Vitamin K
Warfarin inhibits vitamin K epoxide reductase, preventing recycling of vitamin K, which is essential for synthesis of clotting factors II, VII, IX, and X.
Which opioid receptor is primarily responsible for analgesia and euphoria?
Answer: Mu (μ)
Mu (μ) opioid receptors mediate analgesia, euphoria, respiratory depression, and physical dependence — making them the primary target for opioid analgesics.
A patient taking a monoamine oxidase inhibitor (MAOI) should avoid which food to prevent hypertensive crisis?
Answer: Aged cheeses
Aged cheeses contain tyramine. MAOIs block its breakdown, causing excessive norepinephrine release and severe hypertension (cheese reaction).
The first-pass effect refers to a drug being significantly metabolized in the:
Answer: Liver before reaching systemic circulation
First-pass (presystemic) metabolism occurs in the liver after oral absorption; drugs pass through portal circulation and are metabolized before entering systemic circulation.