Pharmacology Drug Classifications and Prototypes 3

Question 1

Captopril is the prototype of which antihypertensive drug class?

Accepted Answer

ACE inhibitors

Answer

Captopril is the prototype ACE inhibitor, blocking conversion of angiotensin I to angiotensin II to lower blood pressure.

Question 2

Which benzodiazepine is considered the prototype of its drug class?

Accepted Answer

Diazepam

Answer

Diazepam (Valium) is the prototype benzodiazepine, enhancing GABA-A receptor activity to produce anxiolytic, sedative, and anticonvulsant effects.

Question 3

Ibuprofen is categorized as a prototype non-selective NSAID. What is its primary mechanism?

Accepted Answer

Non-selective COX-1 and COX-2 inhibition

Answer

Ibuprofen non-selectively inhibits both COX-1 and COX-2 enzymes, reducing prostaglandin synthesis to produce anti-inflammatory and analgesic effects.

Question 4

Atropine is the prototype drug of which class?

Accepted Answer

Anticholinergic (muscarinic antagonist) agents

Answer

Atropine is the prototype anticholinergic agent, competitively blocking muscarinic receptors to increase heart rate and decrease secretions.

Question 5

Which drug is the prototype tetracycline antibiotic?

Accepted Answer

Tetracycline

Answer

Tetracycline is the prototype of the tetracycline class, inhibiting bacterial protein synthesis by binding to the 30S ribosomal subunit.

Pharmacology Practice Test