Persistent Depressive Disorder Persistent Depressive Disorder Treatment & Therapeutic Interventions 2

Question 1

Which SNRI has evidence supporting its use in Persistent Depressive Disorder and is commonly used when SSRIs are ineffective?

Accepted Answer

Venlafaxine

Answer

Venlafaxine, an SNRI, is supported by evidence for chronic depression and is often used after SSRI failure.

Question 2

A patient with PDD is being treated with CBT. Which core cognitive intervention directly addresses the pervasive hopelessness characteristic of PDD?

Accepted Answer

Cognitive restructuring of negative automatic thoughts

Answer

Cognitive restructuring challenges and modifies the negative automatic thoughts and hopeless schemas that sustain chronic depression.

Question 3

What is the main advantage of CBASP over standard CBT for patients with Persistent Depressive Disorder?

Accepted Answer

It directly addresses the interpersonal dysfunction caused by early-onset chronic depression

Answer

CBASP addresses the specific interpersonal and developmental consequences of early-onset chronic depression through situational analysis and disciplined personal involvement.

Question 4

For a patient with PDD who cannot tolerate SSRIs due to sexual side effects, which antidepressant is a reasonable alternative with a different side-effect profile?

Accepted Answer

Bupropion

Answer

Bupropion (NDRI) is associated with lower rates of sexual dysfunction compared to SSRIs and is a reasonable alternative.

Question 5

Which non-pharmacological intervention has emerging evidence as an adjunct for treatment-resistant Persistent Depressive Disorder?

Accepted Answer

Transcranial magnetic stimulation (TMS)

Answer

Transcranial magnetic stimulation (TMS) has received FDA clearance for treatment-resistant depression and shows promise as an adjunct in PDD.

Persistent Depressive Disorder Practice Test

Persistent Depressive Disorder Practice Test

Persistent Depressive Disorder Persistent Depressive Disorder Treatment & Therapeutic Interventions 2