Persistent Depressive Disorder Persistent Depressive Disorder Treatment & Therapeutic Interventions

Question 1

Which class of antidepressant is considered a first-line pharmacological treatment for Persistent Depressive Disorder?

Accepted Answer

Selective serotonin reuptake inhibitors (SSRIs)

Answer

Tricyclic antidepressants (TCAs)

Answer

Monoamine oxidase inhibitors (MAOIs)

Answer

Antipsychotics

Question 2

Which psychotherapy has the strongest evidence base for treating Persistent Depressive Disorder specifically, compared to general depression therapies?

Accepted Answer

Cognitive Behavioral Analysis System of Psychotherapy (CBASP)

Answer

Dialectical Behavior Therapy (DBT)

Answer

Acceptance and Commitment Therapy (ACT)

Answer

Interpersonal Therapy (IPT)

Question 3

A patient with PDD has had an inadequate response to a therapeutic dose of an SSRI for 8 weeks. What is the recommended next step?

Accepted Answer

Augment with an atypical antipsychotic or switch to an SNRI

Answer

Immediately switch to an MAOI

Answer

Discontinue all medications and use therapy alone

Answer

Double the SSRI dose without further evaluation

Question 4

How long should pharmacotherapy typically be continued in a patient with Persistent Depressive Disorder after achieving remission?

Accepted Answer

At least 2 years or long-term

Answer

3 months

Answer

6 months

Answer

Until the patient requests to stop

Question 5

Which therapeutic approach is most effective when combined with antidepressant medication for Persistent Depressive Disorder, according to major clinical trials?

Accepted Answer

Combined pharmacotherapy and psychotherapy

Answer

Medication alone is always superior

Answer

Psychotherapy alone without medication

Answer

Electroconvulsive therapy (ECT) as first-line

Question 6

Behavioral Activation (BA) as a component of CBT for PDD primarily targets which maintaining factor?

Accepted Answer

Avoidance and reduced engagement with rewarding activities

Answer

Cognitive distortions about the future

Answer

Interpersonal conflicts with family members

Answer

Sleep architecture disruption