Persistent Depressive Disorder Persistent Depressive Disorder Treatment & Therapeutic Approaches 1

Question 1

Which class of antidepressants is considered a first-line pharmacological treatment for Persistent Depressive Disorder in the US?

Accepted Answer

Selective serotonin reuptake inhibitors (SSRIs)

Answer

SSRIs are the preferred first-line pharmacotherapy for PDD due to their favorable safety and tolerability profile.

Question 2

Which psychotherapy has the strongest evidence base for treating Persistent Depressive Disorder, specifically developed for chronic depression?

Accepted Answer

Cognitive Behavioral Analysis System of Psychotherapy (CBASP)

Answer

CBASP was specifically designed and validated for chronic depression including PDD, making it the most evidence-based psychotherapy for this condition.

Question 3

Research shows that the most effective treatment for PDD combines which two modalities?

Accepted Answer

Antidepressant medication plus psychotherapy

Answer

Studies consistently show combined antidepressant pharmacotherapy plus psychotherapy produces superior outcomes to either treatment alone for PDD.

Question 4

Which SNRI is commonly used as an alternative to SSRIs for treating PDD?

Accepted Answer

Venlafaxine

Answer

Venlafaxine, an SNRI, is a commonly used alternative to SSRIs for PDD and has demonstrated efficacy in chronic depression.

Question 5

How long should pharmacotherapy typically be continued in PDD to prevent relapse?

Accepted Answer

At least 1 year or indefinitely given chronicity

Answer

Given PDD's chronic nature, guidelines recommend continuing pharmacotherapy for at least 1 year after remission, often indefinitely.

Persistent Depressive Disorder Practice Test

Persistent Depressive Disorder Practice Test

Persistent Depressive Disorder Persistent Depressive Disorder Treatment & Therapeutic Approaches 1