PEBC Diagnostic Procedures 2

Question 1

A patient's serum creatinine is 180 µmol/L and eGFR is 28 mL/min/1.73m². Which CKD stage does this represent?

Accepted Answer

Stage 4 (severe decrease)

Answer

An eGFR of 15–29 mL/min/1.73m² corresponds to CKD Stage 4 (severe decrease in kidney function).

Question 2

Which laboratory finding is most consistent with iron-deficiency anemia?

Accepted Answer

Low serum ferritin, elevated TIBC

Answer

Iron-deficiency anemia is characterized by low serum ferritin (depleted stores) and elevated TIBC (transferrin unsaturated).

Question 3

A pharmacist reviews a patient's ECG and notes a prolonged QTc of 510 ms. Which drug interaction is most likely responsible?

Accepted Answer

Azithromycin + haloperidol

Answer

Both azithromycin and haloperidol independently prolong the QTc interval, and their combination significantly increases the risk of torsades de pointes.

Question 4

A patient's urine dipstick shows 3+ protein and 2+ blood. The most appropriate next diagnostic step is:

Accepted Answer

Urine microscopy and ACR (albumin-to-creatinine ratio)

Answer

Persistent proteinuria and hematuria on dipstick require urine microscopy and ACR to quantify proteinuria and evaluate for glomerular pathology.

Question 5

Which INR range is the therapeutic target for a patient with a mechanical heart valve receiving warfarin?

Accepted Answer

2.5–3.5

Answer

Mechanical heart valves generally require a higher INR target of 2.5–3.5 to prevent thromboembolism.

PEBC - Pharmacy Examining Board of Canada Practice Test

PEBC - Pharmacy Examining Board of Canada Practice Test

PEBC Diagnostic Procedures 2