Parkinson's Trivia 2 — Questions and Answers
Question 1: Which famous boxer was diagnosed with Parkinson's disease in 1984?
- Sugar Ray Leonard
- Muhammad Ali (Correct answer)
- Joe Frazier
- George Foreman
Correct answer: Muhammad Ali
Muhammad Ali was diagnosed with Parkinson's disease in 1984, three years after retiring from boxing.
Question 2: What is the name of the protein that abnormally clumps in the brains of Parkinson's patients?
- Tau
- Amyloid-beta
- Alpha-synuclein (Correct answer)
- TDP-43
Correct answer: Alpha-synuclein
Alpha-synuclein misfolds and aggregates into Lewy bodies, a hallmark of Parkinson's disease pathology.
Question 3: In which decade was the drug levodopa first introduced as a treatment for Parkinson's disease?
- 1950s
- 1960s (Correct answer)
- 1970s
- 1980s
Correct answer: 1960s
Levodopa was introduced in the 1960s and remains the most effective medication for managing Parkinson's motor symptoms.
Question 4: What percentage of Parkinson's cases are estimated to be genetic in origin?
- About 5–10% (Correct answer)
- About 25%
- About 40%
- About 60%
Correct answer: About 5–10%
Approximately 5–10% of Parkinson's cases are linked to identified genetic mutations, while the majority are idiopathic.
Question 5: Which sense is commonly impaired years before motor symptoms appear in Parkinson's disease?
- Vision
- Hearing
- Smell (Correct answer)
- Taste
Correct answer: Smell
Loss of smell (hyposmia or anosmia) is a well-documented prodromal symptom that can precede motor symptoms by years.
Question 6: What does the acronym 'DBS' stand for in Parkinson's treatment?
- Dopamine Boosting System
- Deep Brain Stimulation (Correct answer)
- Direct Brain Surgery
- Dopaminergic Brain Signaling
Correct answer: Deep Brain Stimulation
Deep Brain Stimulation (DBS) involves implanting electrodes to deliver electrical impulses to targeted brain regions, reducing Parkinson's symptoms.
Question 7: Which country has the highest estimated prevalence of Parkinson's disease per capita?
- United States
- China
- Argentina
- Finland (Correct answer)
Correct answer: Finland
Nordic countries, particularly Finland, show among the highest prevalence rates of Parkinson's disease globally, though exact rankings vary by study.
Which famous boxer was diagnosed with Parkinson's disease in 1984?