Parkinson's Parkinson's Treatment and Medications

Question 1

What is the most effective pharmacological treatment for the motor symptoms of Parkinson's disease?

Accepted Answer

Levodopa/carbidopa (Sinemet)

Answer

Amantadine

Answer

Selegiline

Answer

Rivastigmine

Question 2

What is the role of carbidopa when combined with levodopa in Parkinson's treatment?

Accepted Answer

Prevents peripheral conversion of levodopa to dopamine

Answer

Enhances dopamine reuptake

Answer

Blocks dopamine receptors

Answer

Increases levodopa absorption from the gut

Question 3

Which class of medications mimics dopamine by directly stimulating dopamine receptors in Parkinson's treatment?

Accepted Answer

Dopamine agonists

Answer

MAO-B inhibitors

Answer

COMT inhibitors

Answer

Anticholinergics

Question 4

Dyskinesias in Parkinson's disease treatment refer to:

Accepted Answer

Involuntary writhing movements caused by long-term levodopa use

Answer

Freezing of gait episodes

Answer

Medication-induced tremor

Answer

Muscle cramps from dopamine agonists

Question 5

Which surgical treatment for Parkinson's disease involves implanting electrodes in the brain to modulate neural activity?

Accepted Answer

Deep brain stimulation (DBS)

Answer

Pallidotomy

Answer

Thalamotomy

Answer

Focused ultrasound

Question 6

MAO-B inhibitors like selegiline and rasagiline work in Parkinson's disease by:

Accepted Answer

Slowing the breakdown of dopamine in the brain

Answer

Increasing dopamine production

Answer

Blocking dopamine reuptake

Answer

Stimulating dopamine receptors