A patient is diagnosed with Primary Open-Angle Glaucoma (POAG). As an ophthalmic executive, you understand this is the most common form of glaucoma. Which of the following best describes the underlying pathophysiology of this condition?
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A
A sudden and complete blockage of the eye's drainage angle by the iris.
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B
A gradual clogging of the trabecular meshwork, which impedes the outflow of aqueous humor.
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C
Damage to the optic nerve despite intraocular pressure being within the normal range.
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D
An identifiable cause, such as an eye injury or medication, leading to increased eye pressure.