A 45-year-old contact lens wearer presents with a ring-shaped corneal infiltrate and severe pain. Culture reveals Acanthamoeba. What is the most appropriate initial treatment?
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A
Polyhexamethylene biguanide (PHMB) with propamidine
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B
Topical fluoroquinolone monotherapy
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C
Oral acyclovir
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D
Topical natamycin alone