A patient with full decision-making capacity adamantly refuses a life-saving blood transfusion based on deeply held religious beliefs. The patient's family is distraught and urges the Assistant Nurse Manager (ANM) to intervene and administer the transfusion. Which ethical principle must the ANM prioritize in this situation?
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A
Beneficence
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B
Justice
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C
Non-maleficence
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D
Autonomy