ALAT - Assistant Laboratory Animal Technician Regulations and Compliance Questions and Answers

Question 1

Which of the following documents must be submitted to the Office of Laboratory Animal Welfare (OLAW) by an institution to receive Public Health Service (PHS) funding for research involving animals?

Accepted Answer

An Animal Welfare Assurance

Answer

Institutions receiving PHS funds for research involving live vertebrate animals must provide a written Animal Welfare Assurance to OLAW. This document describes the institution's program for the care and use of animals and commits the institution to complying with the PHS Policy, the Guide for the Care and Use of Laboratory Animals, and the Animal Welfare Act regulations.

Question 2

An ALAT notices that a new research protocol involving dogs seems to lack a plan for exercise. According to the Animal Welfare Act (AWA), which entity is responsible for ensuring this requirement is met?

Accepted Answer

The Institutional Animal Care and Use Committee (IACUC)

Answer

The Animal Welfare Act, through the Improved Standards for Laboratory Animals Act (ISLAA) amendment, mandates that research facilities provide exercise for dogs. The Institutional Animal Care and Use Committee (IACUC) is responsible for the oversight of the animal care and use program, which includes reviewing and approving protocols to ensure they comply with all regulations, including the AWA's exercise requirement for dogs.

Question 3

The 'Guide for the Care and Use of Laboratory Animals' is a primary reference document for animal care programs. Which of the following best describes its role in U.S. regulations?

Accepted Answer

It is used by the PHS Policy as a required standard for animal care programs.

Answer

The Public Health Service (PHS) Policy requires that institutions base their animal care and use programs on the 'Guide for the Care and Use of Laboratory Animals'. While not a law itself, its standards are mandated for any institution receiving PHS funding, making it a key component of U.S. animal welfare oversight.

Question 4

Which of the following is NOT a required member of an Institutional Animal Care and Use Committee (IACUC) according to the PHS Policy?

Accepted Answer

A member of the institution's public relations department

Answer

The PHS Policy mandates that an IACUC must have at least five members, including a veterinarian with program responsibility, a practicing scientist, a non-scientist, and a member who is not affiliated with the institution. There is no requirement for a member from the public relations department.

Question 5

A research study intended to support a premarket submission to the FDA must be conducted in compliance with which specific set of regulations designed to ensure the quality and integrity of safety data?

Accepted Answer

Good Laboratory Practices (GLP)

Answer

Good Laboratory Practices (GLP) are regulations that apply to nonclinical laboratory studies supporting applications for research or marketing permits for products regulated by agencies like the FDA. GLPs are intended to ensure the quality and integrity of the safety data by defining requirements for study conduct, personnel, facilities, records, and reporting.

ALAT - Assistant Laboratory Animal Technician Practice Test

ALAT - Assistant Laboratory Animal Technician Practice Test

ALAT - Assistant Laboratory Animal Technician Regulations and Compliance Questions and Answers