ORE Part 1 Pharmacology

Question 1

What is the maximum recommended dose of lidocaine with 1:80,000 adrenaline for a 70kg adult?

Accepted Answer

4.4mg/kg (308mg)

Answer

3.0mg/kg (210mg)

Answer

7.0mg/kg (490mg)

Answer

2.0mg/kg (140mg)

Question 2

Which analgesic is contraindicated in a patient with a history of aspirin-sensitive asthma?

Accepted Answer

Ibuprofen

Answer

Paracetamol

Answer

Codeine

Answer

Tramadol

Question 3

A patient taking metronidazole for a dental infection should be warned about interaction with which substance?

Accepted Answer

Alcohol

Answer

Caffeine

Answer

Dairy products

Answer

Grapefruit juice

Question 4

Which antibiotic is the first-line choice for acute dental infection in a penicillin-allergic patient in the UK?

Accepted Answer

Metronidazole

Answer

Erythromycin

Answer

Clindamycin

Answer

Ciprofloxacin

Question 5

What is the mechanism of action of articaine that makes it unique among dental local anaesthetics?

Accepted Answer

It contains a thiophene ring allowing enhanced tissue diffusion

Answer

It is an ester-type local anaesthetic

Answer

It does not require a vasoconstrictor

Answer

It works on calcium channels rather than sodium channels

Question 6

A patient on long-term prednisolone 10mg daily requires a dental extraction. What consideration is important regarding steroid supplementation?

Accepted Answer

The patient should double their dose for 24 hours

Answer

No supplementation is needed for minor oral surgery

Answer

The patient should stop steroids 48 hours before

Answer

Intravenous hydrocortisone 100mg is always required