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Chemotherapy Administration Flashcards

6 cards from real OCN practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 6 Chemotherapy Administration flashcards as text

  1. Which chemotherapy agent is classified as a vesicant and requires careful monitoring for extravasation?

    Answer: Vincristine

    Vincristine is a vesicant that can cause severe tissue necrosis if it extravasates from the vein.

  2. What is the correct action if extravasation of a vesicant chemotherapy agent is suspected?

    Answer: Stop the infusion immediately and leave the needle in place

    The infusion must be stopped immediately and the needle left in place so residual drug can be aspirated before further intervention.

  3. Which personal protective equipment (PPE) is required when handling hazardous chemotherapy drugs?

    Answer: Double gloves, gown, and eye protection

    NIOSH and ONS guidelines require double chemotherapy-rated gloves, a protective gown, and eye/face protection when handling hazardous drugs.

  4. A patient receiving cisplatin needs prehydration primarily to prevent which toxicity?

    Answer: Nephrotoxicity

    Cisplatin is highly nephrotoxic, and aggressive IV hydration before and after administration is required to protect renal function.

  5. Which route of administration bypasses the blood-brain barrier most effectively for CNS tumors?

    Answer: Intrathecal

    Intrathecal administration delivers chemotherapy directly into the cerebrospinal fluid, bypassing the blood-brain barrier.

  6. What lab value must be assessed before administering methotrexate at high doses?

    Answer: Creatinine clearance/renal function

    High-dose methotrexate requires adequate renal clearance to prevent toxic accumulation; creatinine clearance must be assessed before dosing.

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