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Cancer Treatment Modalities Flashcards

6 cards from real OCN practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 6 Cancer Treatment Modalities flashcards as text

  1. Which of the following is a cell-cycle-specific chemotherapy agent?

    Answer: Vincristine

    Vincristine is cell-cycle-specific, acting in the M phase by binding to tubulin and preventing spindle formation.

  2. What cumulative dose of doxorubicin is associated with the greatest risk of cardiomyopathy?

    Answer: 450–550 mg/m²

    Cardiotoxicity from doxorubicin significantly increases when the cumulative dose exceeds 450–550 mg/m².

  3. A patient receiving irinotecan develops profuse diarrhea within 24 hours of infusion. This is best managed with:

    Answer: Atropine

    Early-onset diarrhea with irinotecan is cholinergic in nature and is treated with atropine.

  4. Which type of radiation therapy delivers a high dose to a small target with steep dose fall-off, minimizing exposure to surrounding tissue?

    Answer: Stereotactic radiosurgery (SRS)

    Stereotactic radiosurgery (SRS) delivers high-dose, precise radiation to a small target using multiple beams that converge, sparing surrounding tissue.

  5. Which of the following is a common dose-limiting toxicity of cisplatin?

    Answer: Nephrotoxicity

    Cisplatin causes significant nephrotoxicity; aggressive hydration and amifostine may be used to minimize renal damage.

  6. Hormonal therapy with tamoxifen is most appropriate for which breast cancer receptor profile?

    Answer: Estrogen receptor-positive

    Tamoxifen is a selective estrogen receptor modulator (SERM) used in estrogen receptor-positive breast cancers.

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