OCN Chemotherapy Administration 2

Question 1

Which chemotherapy drug requires leucovorin rescue to prevent life-threatening toxicity?

Accepted Answer

High-dose methotrexate

Answer

Doxorubicin

Answer

Paclitaxel

Answer

Gemcitabine

Question 2

Doxorubicin has a cumulative lifetime dose limit primarily because of which toxicity?

Accepted Answer

Cardiomyopathy

Answer

Nephrotoxicity

Answer

Neurotoxicity

Answer

Hepatotoxicity

Question 3

What is the purpose of using a CVAD (central venous access device) for chemotherapy?

Accepted Answer

To safely administer vesicants and reduce peripheral vein damage

Answer

To allow the patient to go home sooner

Answer

To reduce drug costs

Answer

To improve oral bioavailability

Question 4

Before administering paclitaxel, the nurse should premedicate with which agents to prevent hypersensitivity reactions?

Accepted Answer

Corticosteroids, diphenhydramine, and an H2 blocker

Answer

Acetaminophen and ibuprofen

Answer

Ondansetron and lorazepam

Answer

Metoclopramide and dexamethasone

Question 5

Which chemotherapy class works by intercalating into DNA strands and inhibiting topoisomerase II?

Accepted Answer

Anthracyclines

Answer

Alkylating agents

Answer

Antimetabolites

Answer

Vinca alkaloids

Question 6

Oral chemotherapy education should stress which of the following to patients?

Accepted Answer

Never handle tablets with bare hands and use safe disposal methods

Answer

Crush tablets to improve absorption

Answer

Share doses with caregivers if they have the same cancer

Answer

Store in the bathroom medicine cabinet for convenience