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OCC Pharmacology & Therapeutics Flashcards

6 cards from real OCC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 6 OCC Pharmacology & Therapeutics flashcards as text

  1. A patient develops a dry cough after starting lisinopril for hypertension. What is the best alternative medication?

    Answer: Angiotensin receptor blocker (ARB) such as losartan

    ACE inhibitor-induced cough is a class effect caused by bradykinin accumulation; switching to an ARB (which doesn't affect bradykinin) eliminates the cough.

  2. Which vaccine is CONTRAINDICATED in immunocompromised patients due to being a live attenuated vaccine?

    Answer: MMR (measles, mumps, rubella)

    MMR is a live attenuated vaccine and can cause disseminated vaccine-strain infection in immunocompromised patients.

  3. Which medication class is first-line for chronic stable angina due to its ability to reduce heart rate, contractility, and myocardial oxygen demand?

    Answer: Beta-blockers

    Beta-blockers are first-line for chronic stable angina because they reduce heart rate and contractility, lowering myocardial oxygen demand and decreasing anginal episodes.

  4. A patient with gout has frequent attacks and is started on allopurinol. What is the mechanism of allopurinol?

    Answer: Inhibits xanthine oxidase to reduce uric acid production

    Allopurinol is a xanthine oxidase inhibitor that blocks the conversion of hypoxanthine and xanthine to uric acid, reducing uric acid production.

  5. Which anticoagulant requires no routine lab monitoring and directly inhibits thrombin (Factor IIa)?

    Answer: Dabigatran (Pradaxa)

    Dabigatran is a direct thrombin (Factor IIa) inhibitor that provides predictable anticoagulation without routine INR monitoring.

  6. A patient on prednisone long-term should be monitored for which common adverse effects?

    Answer: Hyperglycemia, osteoporosis, hypertension, and adrenal suppression

    Long-term corticosteroid use causes hyperglycemia, bone loss (osteoporosis), hypertension, weight gain, and suppresses the HPA axis.

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