OCC OCC Pharmacology & Therapeutics 1

Question 1

A DO prescribes a patient metformin for type 2 diabetes. Which mechanism of action best describes metformin?

Accepted Answer

Decreases hepatic glucose production and improves insulin sensitivity

Answer

Stimulates pancreatic beta cells to release insulin

Answer

Blocks glucose reabsorption in the renal tubule

Answer

Inhibits alpha-glucosidase to slow carbohydrate absorption

Question 2

Which drug interaction results in increased risk of bleeding when warfarin is combined with aspirin?

Accepted Answer

Additive anticoagulant and antiplatelet effect increases hemorrhagic risk

Answer

Aspirin decreases warfarin metabolism causing toxicity

Answer

Aspirin increases warfarin protein binding reducing effect

Answer

Warfarin inhibits aspirin absorption

Question 3

A patient on a fluoroquinolone antibiotic develops tendon pain. Which tendon is most commonly affected?

Accepted Answer

Achilles tendon

Answer

Patellar tendon

Answer

Rotator cuff

Answer

Biceps tendon

Question 4

Which class of antihypertensive medication is contraindicated in bilateral renal artery stenosis?

Accepted Answer

ACE inhibitors and ARBs

Answer

Beta-blockers

Answer

Calcium channel blockers

Answer

Alpha-blockers

Question 5

Which Schedule II controlled substance requires a written or electronic prescription and cannot be refilled?

Accepted Answer

Oxycodone

Answer

Hydrocodone combination products (low dose)

Answer

Tramadol

Answer

Carisoprodol

Question 6

A patient taking a statin develops myalgias with markedly elevated CK levels. What is the most appropriate next step?

Accepted Answer

Discontinue the statin immediately and monitor renal function

Answer

Reduce the dose and continue therapy

Answer

Add CoQ10 and continue the statin

Answer

Switch to a higher potency statin