NTP Chronic Disease & Nutrition 3

Question 1

In autoimmune conditions, which gut-related mechanism is considered a primary driver of immune dysregulation?

Accepted Answer

Increased intestinal permeability (leaky gut)

Answer

Increased intestinal permeability allows antigens to enter systemic circulation, triggering immune responses that can cross-react with self-tissue.

Question 2

Which omega-3 fatty acid is most directly responsible for producing anti-inflammatory resolvins and protectins?

Accepted Answer

Docosahexaenoic acid (DHA)

Answer

DHA is the primary substrate for synthesis of resolvins and protectins, lipid mediators that actively resolve inflammation.

Question 3

A client with hypothyroidism is most likely to have suboptimal levels of which nutrient critical for thyroid hormone synthesis?

Accepted Answer

Iodine

Answer

Iodine is a structural component of thyroxine (T4) and triiodothyronine (T3), making it essential for thyroid hormone production.

Question 4

Which dietary intervention has the strongest evidence for reducing systolic blood pressure?

Accepted Answer

Following the DASH diet with sodium restriction

Answer

The DASH diet combined with sodium restriction consistently produces clinically significant reductions in blood pressure across populations.

Question 5

Metabolic syndrome is defined by a cluster of conditions that include all of the following EXCEPT:

Accepted Answer

High HDL cholesterol

Answer

Metabolic syndrome criteria include low HDL (not high HDL), along with elevated glucose, triglycerides, blood pressure, and waist circumference.

(NTP) Nutritional Therapy Practitioner Practice Test