NRP Thermoregulation and Temperature Management 2

Question 1

Therapeutic hypothermia (controlled cooling) is the established neuroprotective treatment for which neonatal condition?

Accepted Answer

Hypoxic-ischemic encephalopathy (HIE)

Answer

Therapeutic hypothermia is the standard neuroprotective treatment for moderate-to-severe hypoxic-ischemic encephalopathy (HIE) in term and near-term neonates.

Question 2

What is the standard target core temperature for whole-body therapeutic hypothermia in eligible neonates?

Accepted Answer

33-34°C (91.4-93.2°F)

Answer

Clinical protocols target a core temperature of 33-34°C (91.4-93.2°F) during therapeutic hypothermia to reduce secondary neuronal injury after HIE.

Question 3

For how long is therapeutic hypothermia typically maintained in eligible neonates with HIE?

Accepted Answer

72 hours

Answer

Major randomized controlled trials established 72 hours as the standard duration for therapeutic hypothermia, after which gradual rewarming is initiated.

Question 4

Which of the following clinical findings may indicate hypothermia in a newborn?

Accepted Answer

Poor feeding, lethargy, and cold extremities

Answer

Hypothermic newborns typically present with poor feeding, lethargy, cold extremities, and pallor due to peripheral vasoconstriction and decreased metabolic activity.

Question 5

Hyperthermia (temperature >38°C) during or after neonatal resuscitation is associated with which outcome?

Accepted Answer

Increased risk of brain injury and worsened outcomes

Answer

Hyperthermia increases excitotoxicity and metabolic demands in injured brain tissue, and is associated with worsened neurological outcomes, particularly after perinatal asphyxia.

NRP - Neonatal Resuscitation Program Practice Test

NRP - Neonatal Resuscitation Program Practice Test

NRP Thermoregulation and Temperature Management 2