NPS NPS Respiratory Management 2 — Questions and Answers
Question 1: What is the primary advantage of nasal CPAP (nCPAP) over mechanical ventilation for preterm neonates with mild-moderate RDS?
- Higher oxygen delivery
- Avoidance of intubation and reduced BPD risk (Correct answer)
- More precise tidal volume control
- Easier nursing care
Correct answer: Avoidance of intubation and reduced BPD risk
nCPAP avoids the trauma of intubation and reduces the incidence of bronchopulmonary dysplasia by recruiting alveoli non-invasively.
Question 2: During neonatal resuscitation, the initial FiO2 for a term newborn should be:
- 21% (room air) (Correct answer)
- 40%
- 60%
- 100%
Correct answer: 21% (room air)
Current NRP guidelines recommend starting resuscitation of term newborns with room air (21% O2), titrating upward based on pulse oximetry.
Question 3: A neonate develops a sudden deterioration on mechanical ventilation. The NPS performs a DOPE assessment. What does 'D' stand for?
- Decreased breath sounds
- Displacement of the ETT (Correct answer)
- Drug effect
- Diaphragm weakness
Correct answer: Displacement of the ETT
The DOPE mnemonic for sudden deterioration on a ventilator stands for Displacement, Obstruction, Pneumothorax, and Equipment failure.
Question 4: What is the minimum recommended positive end-expiratory pressure (PEEP) for mechanically ventilated neonates with RDS?
- 1–2 cmH2O
- 3–4 cmH2O
- 4–6 cmH2O (Correct answer)
- 8–10 cmH2O
Correct answer: 4–6 cmH2O
A PEEP of 4–6 cmH2O is recommended for neonates with RDS to maintain functional residual capacity and prevent alveolar collapse between breaths.
Question 5: Meconium aspiration syndrome (MAS) is characterized by which pathophysiological mechanism?
- Surfactant excess with alveolar overdistension
- Airway obstruction, surfactant inactivation, and chemical pneumonitis (Correct answer)
- Pulmonary hypoplasia from oligohydramnios
- Bacterial pneumonia from GBS
Correct answer: Airway obstruction, surfactant inactivation, and chemical pneumonitis
MAS causes a ball-valve airway obstruction, inactivates surfactant, triggers chemical pneumonitis, and often leads to pulmonary hypertension.
Question 6: A 32-week neonate is being weaned from mechanical ventilation. Which post-extubation support is most likely to prevent re-intubation?
- Low-flow nasal cannula at 0.5 LPM
- Heated humidified high-flow nasal cannula (HHHFNC)
- Nasal CPAP at 5–7 cmH2O (Correct answer)
- Supplemental O2 via hood
Correct answer: Nasal CPAP at 5–7 cmH2O
Post-extubation nasal CPAP at 5–7 cmH2O is the most effective respiratory support for preterm neonates to maintain lung recruitment and prevent apnea.
What is the primary advantage of nasal CPAP (nCPAP) over mechanical ventilation for preterm neonates with mild-moderate RDS?