NPS NPS Pharmacology and Medications 1

Question 1

What is the recommended dose of caffeine citrate loading dose for apnea of prematurity in neonates?

Accepted Answer

20 mg/kg IV

Answer

Caffeine citrate loading dose for apnea of prematurity is 20 mg/kg IV, followed by a maintenance dose of 5–10 mg/kg/day.

Question 2

Which surfactant is administered intratracheally as a natural bovine-derived preparation for neonatal RDS?

Accepted Answer

All of the above

Answer

Beractant, calfactant, and poractant alfa are all natural animal-derived surfactants approved for intratracheal administration in neonatal RDS.

Question 3

When administering prostaglandin E1 (alprostadil) to a neonate with ductal-dependent congenital heart disease, which adverse effect requires immediate readiness?

Accepted Answer

Apnea

Answer

Apnea is the most critical adverse effect of prostaglandin E1 infusion in neonates, requiring intubation readiness at the bedside.

Question 4

What is the correct dose of epinephrine for neonatal cardiac arrest via the endotracheal route?

Accepted Answer

0.05–0.1 mg/kg

Answer

The ET dose of epinephrine in neonatal resuscitation is 0.05–0.1 mg/kg (higher than IV) due to poor absorption via the tracheal route.

Question 5

A preterm neonate requires indomethacin for PDA closure. Which lab value must be monitored most closely?

Accepted Answer

Serum creatinine

Answer

Indomethacin reduces renal prostaglandin synthesis, causing decreased GFR and elevated serum creatinine; renal function must be monitored closely.

NPS - Neonatal Pediatric Specialist Practice Test

NPS - Neonatal Pediatric Specialist Practice Test

NPS NPS Pharmacology and Medications 1