NPS NPS Pharmacology and Medications 2

Question 1

A 28-week neonate receives vancomycin for suspected sepsis. Which pharmacokinetic parameter is most commonly monitored to guide dosing?

Accepted Answer

AUC/MIC ratio

Answer

Peak concentration

Answer

Half-life

Answer

Volume of distribution

Question 2

Dexamethasone is used postnatally in premature neonates primarily to treat which condition?

Accepted Answer

Bronchopulmonary dysplasia

Answer

Hypoglycemia

Answer

Intraventricular hemorrhage

Answer

Necrotizing enterocolitis

Question 3

What is the maximum safe concentration of dextrose that should be administered via a peripheral IV in a neonate?

Accepted Answer

D12.5W (12.5%)

Answer

D5W (5%)

Answer

D10W (10%)

Answer

D15W (15%)

Question 4

A pediatric patient in status asthmaticus fails initial bronchodilator therapy. Which IV medication is administered next?

Accepted Answer

Magnesium sulfate

Answer

Aminophylline

Answer

Terbutaline IV

Answer

Ketamine

Question 5

Which medication is used to treat neonatal seizures as first-line therapy in the US?

Accepted Answer

Phenobarbital

Answer

Levetiracetam

Answer

Fosphenytoin

Answer

Lorazepam

Question 6

A neonate with persistent pulmonary hypertension (PPHN) fails conventional therapy. Which inhaled medication is indicated?

Accepted Answer

Nitric oxide (iNO)

Answer

Epoprostenol

Answer

Sildenafil

Answer

Bosentan