NLE Pharmacology and Medication Management

Question 1

What term describes the study of how drugs move through the body, including absorption, distribution, metabolism, and excretion?

Accepted Answer

Pharmacokinetics

Answer

Pharmacokinetics describes the movement of drugs through the body via absorption, distribution, metabolism, and excretion (ADME).

Question 2

Which route of drug administration provides the fastest onset of action?

Accepted Answer

Intravenous

Answer

Intravenous (IV) administration delivers drugs directly into the bloodstream, bypassing absorption and providing the fastest onset.

Question 3

A medication has a 'narrow therapeutic index.' This means:

Accepted Answer

There is a small difference between therapeutic and toxic doses

Answer

A narrow therapeutic index means the margin between the effective dose and the toxic dose is small, requiring careful monitoring.

Question 4

Naloxone is classified as an opioid antagonist because it:

Accepted Answer

Blocks opioid receptor sites and reverses opioid effects

Answer

Naloxone competitively blocks opioid receptors, reversing respiratory depression and other opioid effects.

Question 5

The 'first-pass effect' refers to:

Accepted Answer

Hepatic metabolism of a drug before it reaches systemic circulation

Answer

The first-pass effect occurs when orally administered drugs are metabolized by the liver before reaching systemic circulation, reducing bioavailability.

NLE - National Licensure Examination Practice Test

NLE - National Licensure Examination Practice Test

NLE Pharmacology and Medication Management