Neurologists Exam Neurologists Exam Neurodegenerative & Movement Disorders

Question 1

The triad of resting tremor, rigidity, and bradykinesia is classic for which neurodegenerative disorder?

Accepted Answer

Parkinson's disease

Answer

Huntington's disease

Answer

Multiple sclerosis

Answer

Amyotrophic lateral sclerosis

Question 2

Which protein aggregate is the pathological hallmark found in Lewy body dementia and Parkinson's disease?

Accepted Answer

Alpha-synuclein (Lewy bodies)

Answer

Tau neurofibrillary tangles

Answer

TDP-43 inclusions

Answer

Amyloid-beta plaques

Question 3

Huntington's disease is caused by a CAG trinucleotide repeat expansion in which gene?

Accepted Answer

HTT (huntingtin)

Answer

ATXN1 (ataxin-1)

Answer

FMR1 (fragile X)

Answer

C9orf72

Question 4

Which finding on neuroimaging is most characteristic of multiple system atrophy (MSA-P subtype)?

Accepted Answer

Putaminal atrophy with T2 hypointensity and rim sign

Answer

Hippocampal atrophy on MRI

Answer

White matter hyperintensities on FLAIR

Answer

Caudate atrophy on MRI

Question 5

The DaTscan (dopamine transporter scan) is used to differentiate Parkinson's disease from which condition?

Accepted Answer

Essential tremor

Answer

Huntington's disease

Answer

Wilson's disease

Answer

Tourette syndrome

Question 6

Which medication is considered the gold standard for symptomatic treatment of Parkinson's disease motor symptoms?

Accepted Answer

Levodopa/carbidopa

Answer

Bromocriptine alone

Answer

Amantadine alone

Answer

Pramipexole alone