NBDHE Oral Pathology and Disease Recognition Flashcards

Oral squamous cell carcinoma most commonly arises at which intraoral site?

Answer: Lateral border of tongue and floor of mouth

The lateral border of the tongue and floor of the mouth are the most common sites for oral squamous cell carcinoma due to pooling of carcinogens.

The two most significant risk factors for oral squamous cell carcinoma are:

Answer: Tobacco use and alcohol consumption

Tobacco use and alcohol consumption are the primary risk factors for oral squamous cell carcinoma, and their combined effect is synergistic.

A periapical abscess typically appears on a radiograph as:

Answer: A radiolucent area at the root apex

A periapical abscess appears as a radiolucent area at the tooth root apex because infection causes local bone destruction.

Pemphigus vulgaris is an autoimmune condition characterized by a positive Nikolsky sign and:

Answer: Intraepithelial flaccid bullae that rupture easily

Pemphigus vulgaris involves IgG autoantibodies against desmoglein proteins, causing intraepithelial acantholysis and flaccid bullae that rupture to form painful erosions.

The most recognizable form of oral lichen planus presents as:

Answer: White interlacing lines (Wickham's striae)

The reticular form of oral lichen planus is the most common presentation, characterized by white interlacing lines called Wickham's striae on the buccal mucosa.

Oral Kaposi's sarcoma most commonly presents on the palate and is strongly associated with:

Answer: HIV/AIDS

Oral Kaposi's sarcoma is an AIDS-defining malignancy appearing as red, purple, or brown macules or nodules most often on the hard palate of HIV-positive patients.