NBDE Ultimate 2

Question 1

Which antibiotic is the first-line treatment for odontogenic infections in non-penicillin-allergic patients?

Accepted Answer

Amoxicillin

Answer

Amoxicillin is the first-line antibiotic for odontogenic infections due to its broad-spectrum coverage of oral flora and good bioavailability.

Question 2

Aspirin irreversibly inhibits cyclooxygenase enzymes. This type of inhibition is best classified as:

Accepted Answer

Covalent (irreversible) inhibition

Answer

Aspirin acetylates a serine residue on COX via a covalent bond, permanently inactivating the enzyme for the platelet's lifetime.

Question 3

Which microorganism is the primary etiologic agent of early childhood caries (ECC)?

Accepted Answer

Streptococcus mutans

Answer

Streptococcus mutans is the primary pathogen in ECC due to its acidogenicity, aciduricity, and ability to synthesize extracellular polysaccharides for biofilm adherence.

Question 4

A white, non-wipeable lesion on the floor of the mouth of a 60-year-old smoker is best classified as:

Accepted Answer

Leukoplakia

Answer

Leukoplakia is a clinical diagnosis for white plaques that cannot be scraped off and cannot be characterized as any other definable lesion.

Question 5

Which analgesic is classified as a selective COX-2 inhibitor?

Accepted Answer

Celecoxib

Answer

Celecoxib selectively inhibits COX-2, reducing inflammation with less GI toxicity than non-selective NSAIDs that also block COX-1.

NBDE - National Board Dental Examination Practice Test

NBDE - National Board Dental Examination Practice Test

NBDE Ultimate 2