A pharmacist is assessing a patient with heart failure who is taking an NSAID for arthritis pain. What is the primary concern in the care planning process?
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A
NSAIDs reduce the efficacy of ACE inhibitors and promote sodium retention, worsening heart failure
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B
NSAIDs cause hyperkalemia that directly damages myocardial cells
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C
NSAIDs are converted to toxic metabolites in heart failure patients
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D
NSAIDs are contraindicated only in patients with ejection fraction above 60%