A patient with heart failure (EF 35%) is started on carvedilol. Which clinical response would indicate the drug should be titrated up sooner than planned?
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A
Heart rate decreased from 88 to 72 bpm
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B
Blood pressure dropped from 130/80 to 100/65 mmHg
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C
Patient reports improved dyspnea on exertion at 2 weeks
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D
Peripheral edema worsened at week 1