MTM Respiratory Disease Management

Question 1

According to GINA guidelines, what is the preferred first-line controller therapy for mild persistent asthma in adults?

Accepted Answer

Inhaled corticosteroid (ICS)

Answer

Long-acting beta-agonist (LABA) alone

Answer

Oral leukotriene receptor antagonist (LTRA)

Answer

Short-acting beta-agonist (SABA) as needed only

Question 2

Which spirometry finding confirms a diagnosis of COPD per GOLD guidelines?

Accepted Answer

FEV1/FVC ratio < 0.70 post-bronchodilator

Answer

Peak expiratory flow variability > 20%

Answer

FVC < 80% predicted

Answer

FEV1 < 50% predicted

Question 3

A patient using a metered-dose inhaler (MDI) reports poor symptom control. Which inhaler technique error MOST reduces drug delivery to the lungs?

Accepted Answer

Inhaling too rapidly through the MDI

Answer

Exhaling fully before actuation

Answer

Holding breath for 10 seconds after inhalation

Answer

Using a spacer device

Question 4

Which combination inhaler is most appropriate as initial maintenance therapy for a COPD patient classified as GOLD Group B?

Accepted Answer

LABA/LAMA combination

Answer

ICS alone

Answer

LAMA monotherapy

Answer

Triple therapy with ICS/LABA/LAMA

Question 5

An MTM pharmacist is counseling a patient who has both asthma and GERD. Which asthma medication may worsen GERD symptoms?

Accepted Answer

Theophylline

Answer

Inhaled corticosteroids

Answer

Montelukast

Answer

Cromolyn sodium

Question 6

What is the mechanism of action of tiotropium (Spiriva)?

Accepted Answer

Muscarinic receptor antagonism

Answer

Beta-2 receptor agonism

Answer

Leukotriene receptor antagonism

Answer

Phosphodiesterase-4 inhibition

Question 7

A patient requiring a short course of oral corticosteroids for an acute asthma exacerbation asks about side effects. Which adverse effect occurs MOST rapidly with short-term systemic steroid use?

Accepted Answer

Hyperglycemia

Answer

Cataracts

Answer

Osteoporosis

Answer

Adrenal insufficiency