MTM Behavioral Health Pharmacotherapy 4

Question 1

Which antiepileptic mood stabilizer requires monitoring for Stevens-Johnson syndrome, particularly in Asian patients carrying the HLA-B*1502 allele?

Accepted Answer

Carbamazepine

Answer

Carbamazepine is strongly associated with Stevens-Johnson syndrome in patients with the HLA-B*1502 allele, which is prevalent in Asian populations; genetic testing is recommended before use.

Question 2

An MTM pharmacist identifies that a patient with PTSD is taking prazosin. What is the primary indication for this medication in PTSD?

Accepted Answer

Treating trauma-related nightmares and sleep disturbances

Answer

Prazosin, an alpha-1 adrenergic blocker, reduces noradrenergic activity during sleep and is used off-label to reduce trauma-related nightmares and improve sleep quality in PTSD.

Question 3

A patient develops tardive dyskinesia after years of haloperidol use. Which medication is FDA-approved to treat this movement disorder?

Accepted Answer

Valbenazine

Answer

Valbenazine (Ingrezza) and deutetrabenazine are FDA-approved VMAT2 inhibitors indicated for the treatment of tardive dyskinesia.

Question 4

Which medication is considered first-line pharmacotherapy for attention-deficit/hyperactivity disorder (ADHD) in adults?

Accepted Answer

Amphetamine salts or methylphenidate

Answer

Stimulant medications (amphetamines and methylphenidate) are first-line pharmacotherapy for adult ADHD due to superior efficacy compared to non-stimulant alternatives.

Question 5

A patient on lithium is started on ibuprofen for arthritis pain. What effect will this interaction have on lithium levels?

Accepted Answer

Lithium levels will increase due to decreased renal clearance

Answer

NSAIDs inhibit prostaglandin-mediated renal blood flow, reducing renal lithium clearance and increasing serum lithium levels, potentially causing toxicity.

(MTM) Medication Therapy Management Certification for Pharmacists Practice Test

(MTM) Medication Therapy Management Certification for Pharmacists Practice Test

MTM Behavioral Health Pharmacotherapy 4